USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: DC1I2_HUMAN USC-OGP 2-DE database:  DC1I2_HUMAN DC1I2_HUMAN General information about the entry View entry in simple text format Entry name DC1I2_HUMAN Primary accession number Q13409 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Cytoplasmic dynein 1 intermediate chain 2; AltName: Full=Cytoplasmic dynein intermediate chain 2; AltName: Full=Dynein intermediate chain 2, cytosolic; Short=DH IC-2;. Gene name Name=DYNC1I2 Synonyms=DNCI2, DNCIC2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1118: pI=5.28; Mw=86732 Cross-references UniProtKB/Swiss-Prot Q13409; DC1I2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DC1I2_HUMAN Primary accession number Q13409 Secondary accession number(s) B7ZA04 D3DPD4 D3DPD5 D3DPD6 Q32LY9 Q53S84 Q5BJF8 Q7Z4X1 Q96NG7 Q96S87 Q9BXZ5 Q9NT58 Sequence was last modified on  September 19, 2002 (version 3) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=Cytoplasmic dynein 1 intermediate chain 2; AltName: Full=Cytoplasmic dynein intermediate chain 2; AltName: Full=Dynein intermediate chain 2, cytosolic; Short=DH IC-2; Gene name Name=DYNC1I2 Synonyms=DNCI2, DNCIC2 Encoded on Name=DYNC1I2; Synonyms=DNCI2, DNCIC2 Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Dynein; Host-virus interaction; Microtubule; Motor protein; Phosphoprotein; Reference proteome; Repeat; Transport; WD repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF134477; AAP97254.1; -; mRNA EMBL AF250307; AAK37426.1; -; mRNA EMBL AY037160; AAK67638.1; -; mRNA EMBL BT007130; AAP35794.1; -; mRNA EMBL AK055491; BAB70932.1; -; mRNA EMBL AK316119; BAH14490.1; -; mRNA EMBL AL137519; CAB70785.1; -; mRNA EMBL BX537412; CAD97654.1; -; mRNA EMBL AC064826; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC068039; AAY24133.1; -; Genomic_DNA EMBL CH471058; EAX11202.1; -; Genomic_DNA EMBL CH471058; EAX11204.1; -; Genomic_DNA EMBL CH471058; EAX11206.1; -; Genomic_DNA EMBL CH471058; EAX11207.1; -; Genomic_DNA EMBL CH471058; EAX11208.1; -; Genomic_DNA EMBL CH471058; EAX11209.1; -; Genomic_DNA EMBL BC091498; AAH91498.1; -; mRNA EMBL BC109375; AAI09376.1; -; mRNA EMBL BC015038; AAH15038.1; -; mRNA EMBL U39575; AAA89166.1; ALT_SEQ; mRNA CCDS CCDS46450.1; -. [Q13409-1]; . CCDS CCDS63054.1; -. [Q13409-7]; . CCDS CCDS63056.1; -. [Q13409-3]; . CCDS CCDS63057.1; -. [Q13409-6]; . CCDS CCDS82533.1; -. [Q13409-2]; . PIR T46365; T46365; . RefSeq NP_001258714.1; NM_001271785.1. [Q13409-1]; . RefSeq NP_001258715.1; NM_001271786.1. [Q13409-7]; . RefSeq NP_001258716.1; NM_001271787.1. [Q13409-7]; . RefSeq NP_001258717.1; NM_001271788.1. [Q13409-3]; . RefSeq NP_001258718.1; NM_001271789.1. [Q13409-3]; . RefSeq NP_001258719.1; NM_001271790.1. [Q13409-6]; . RefSeq NP_001307811.1; NM_001320882.1. [Q13409-2]; . RefSeq NP_001307812.1; NM_001320883.1. [Q13409-2]; . RefSeq NP_001307813.1; NM_001320884.1. [Q13409-6]; . RefSeq NP_001369.1; NM_001378.2. [Q13409-1]; . UniGene Hs.546250; -; . PDB 5JPW; NMR; -; A/B=134-154 PDBsum 5JPW; -; . ProteinModelPortal Q13409; -; . SMR Q13409; -; . BioGrid 108119; 61; . IntAct Q13409; 28; . MINT MINT-5004520; -; . STRING 9606.ENSP00000380308; -; . iPTMnet Q13409; -; . PhosphoSitePlus Q13409; -; . DMDM 23503058; -; . REPRODUCTION-2DPAGE IPI00827813; -; . EPD Q13409; -; . MaxQB Q13409; -; . PaxDb Q13409; -; . PeptideAtlas Q13409; -; . PRIDE Q13409; -; . DNASU 1781; -; . Ensembl ENST00000340296; ENSP00000339430; ENSG00000077380. [Q13409-3]; . Ensembl ENST00000397119; ENSP00000380308; ENSG00000077380. [Q13409-1]; . Ensembl ENST00000409197; ENSP00000386397; ENSG00000077380. [Q13409-3]; . Ensembl ENST00000409317; ENSP00000386591; ENSG00000077380. [Q13409-2]; . Ensembl ENST00000409453; ENSP00000386886; ENSG00000077380. [Q13409-5]; . Ensembl ENST00000409773; ENSP00000386415; ENSG00000077380. [Q13409-1]; . Ensembl ENST00000410079; ENSP00000386522; ENSG00000077380. [Q13409-7]; . Ensembl ENST00000508530; ENSP00000423339; ENSG00000077380. [Q13409-6]; . GeneID 1781; -; . KEGG hsa:1781; -; . UCSC uc002uha.3; human. [Q13409-1]; . CTD 1781; -; . GeneCards DYNC1I2; -; . HGNC HGNC:2964; DYNC1I2; . HPA CAB033836; -; . HPA HPA040619; -; . HPA HPA053987; -; . MIM 603331; gene; . neXtProt NX_Q13409; -; . OpenTargets ENSG00000077380; -; . PharmGKB PA27435; -; . eggNOG KOG1587; Eukaryota; . eggNOG ENOG410XQ99; LUCA; . GeneTree ENSGT00730000110228; -; . HOVERGEN HBG004083; -; . InParanoid Q13409; -; . KO K10415; -; . OMA INCHAAV; -; . OrthoDB EOG091G038G; -; . PhylomeDB Q13409; -; . TreeFam TF300553; -; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-2565942; Regulation of PLK1 Activity at G2/M Transition; . Reactome R-HSA-380259; Loss of Nlp from mitotic centrosomes; . Reactome R-HSA-380270; Recruitment of mitotic centrosome proteins and complexes; . Reactome R-HSA-380284; Loss of proteins required for interphase microtubule organization from the centrosome; . Reactome R-HSA-5620912; Anchoring of the basal body to the plasma membrane; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811436; COPI-independent Golgi-to-ER retrograde traffic; . Reactome R-HSA-8854518; AURKA Activation by TPX2; . SignaLink Q13409; -; . ChiTaRS DYNC1I2; human; . GeneWiki DYNC1I2; -; . GenomeRNAi 1781; -; . PRO PR:Q13409; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000077380; -; . ExpressionAtlas Q13409; baseline and differential; . Genevisible Q13409; HS; . GO GO:0005813; C:centrosome; IDA:UniProtKB; . GO GO:0005737; C:cytoplasm; NAS:UniProtKB; . GO GO:0005868; C:cytoplasmic dynein complex; IEA:InterPro; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0031982; C:vesicle; IDA:UniProtKB; . GO GO:0003777; F:microtubule motor activity; NAS:UniProtKB; . GO GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome; . GO GO:0097711; P:ciliary basal body docking; TAS:Reactome; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0007018; P:microtubule-based movement; NAS:UniProtKB; . GO GO:0016032; P:viral process; IEA:UniProtKB-KW; . Gene3D 2.130.10.10; -; 1; . InterPro IPR025956; DYNC1I1/DYNC1I2; . InterPro IPR015943; WD40/YVTN_repeat-like_dom; . InterPro IPR001680; WD40_repeat; . InterPro IPR017986; WD40_repeat_dom; . Pfam PF11540; Dynein_IC2; 1; . Pfam PF00400; WD40; 1; . SMART SM00320; WD40; 5; . SUPFAM SSF50978; SSF50978; 1; . PROSITE PS50294; WD_REPEATS_REGION; 1; .

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